Unfortunately, these vigilantes can enter the fallopian tubes and pick off sperm before they have had a chance to meet the egg.
When there is endometriosis present, there are increased numbers of macrophages 5 which become more active and go on their seek and destroy missions with great vigor. Macrophages are large cells which mop up cellular debris and bacteria and other foreign material one of their jobs is to kill off sperm that swim all the way out of the tubes and into the abdomen. prostaglandins, proteolytic enzymes and cytokines. 2Įndometriosis is characterized by a low-grade inflammation in the pelvis, which manifests as an increase in peritoneal fluid, increased number of macrophages and their secretions, i.e. Magnetic resonance imaging (MRI) has revealed a high correlation between endometriosis and adenomyosis in first-degree relatives. There is likely a genetic component since patients with an affected mother or siblings are more likely to have severe endometriosis than those without affected relatives. A quarter of the women attending IVF clinics have endometriosis. This is two to three times the rate of infertility in the general population. Adenomyosis is the term used for endometrial tissue appearing in the myometrium (muscle layer) of the uterine wall.Įndometriosis affects approximately 6–7% of all females, 30–40% of whom are infertile. Rarely, endometrial tissue can be found in other locations in the body. The disease is defined by the presence of endometrial tissue somewhere in the pelvic cavity but outside the uterus. This is due in part to the increasing frequency with which diagnostic surgery is carried out but also to deferred child-bearing and to increasing levels of environmental pollutants. Endometriosis is a not an uncommon diagnosis in recent times.
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